Professor, Biomedical Engineering
lkuhn@uchc.edu | |
Phone | 860-679-3922 |
Mailing Address | UConn Health Center 263 Farmington Ave., MC 1721 Farmington, CT 06030 |
Campus | Farmington |
Google Scholar Link |
Brief Bio
Dr. Kuhn’s laboratory works at the interface of materials science and medicine, and her research spans fundamental studies to translational research and clinical use. She has an expertise in biomaterials and drug delivery and bone regeneration that she gained while working in industry and at UConn Health. She is funded by the National Institutes of Health to develop customized bone grafts for older patients that include controlled release of anti-senescence drugs to rejuvenate bone healing in the elderly. She is Director of the Beekley Lab for Biosymmetrix since Spring 2021, which provides 3D printed personalized breast prostheses for breast cancer survivors. Dr Kuhn is grateful for the funding from the Connecticut Breast Health Initiative and the Beekley Family Foundation for the breast prosthetic project.
Dr. Kuhn and the clinicians at the Carole and Ray Neag Comprehensive Cancer Center are working together to provide improved prosthetics for women that have undergone mastectomy without reconstruction. The prosthetics are produced in the Beekley Lab for Biosymmetrix at UConn Health and are available free of charge at this time (2024).
- Design of implantable drug delivery systems for localized, controlled release of therapeutics.
- 3D Bioprinting custom devices for cancer patients.
- Medical product standards writing for the American Society of Testing and Materials (ASTM).
Project 1: Increasing the rate of bone repair in elderly women through pre-clinical testing of anti-aging drugs delivered by modified bone graft materials. With NIH R01 funding, Professor Kuhn is testing promising therapeutic compounds in aged mouse models of bone injury and repair to identify those that optimize rapid repair of bone defects in craniofacial injuries.
Project 2: Improving the outcomes for adolescents that have broken bones which involve the growth plate and lead to limb shortening and malformation. Professor Kuhn has developed a mouse model for growth plate injuries that uses transgenic mice with fluorescent collagen reporters that allows her to discriminate between promising therapeutics for cartilage repair after growth plate injury. She is collaborating with Professor Yupeng Chen from UConn Storrs on this project.
Project 3: Increasing the self-confidence, comfort, and appearance of breast cancer survivors through 3D-printed breast prosthetics. Customized prosthetics made of a silicone mesh provide unprecedented comfort and customization.
Project 4: Esophageal repair device. Together with Dr. Christine Finck, MD (Connecticut Children’s Medical Center), Professor Kuhn has co-founded Esophadex, Inc and is raising capital to support the development of a 4-in-1 esophageal repair device that will eliminate the multiple surgeries with anesthesia in children under 5 years old with esophageal malformation or injury.
Dr. Liisa Kuhn trains the next generation of scientists by advising undergraduate, graduate, and postdoctoral trainees and giving lectures in her own courses and others. She developed and taught the UConn School of Engineering Biomedical Engineering core course called BME 4710/5700 Biomaterials and Tissue Engineering for nearly a decade and then transitioned to teaching Controlling Stem Cells with Biomaterials (BME 4985-003/BME 6086-004). For the last four years, she serves as the course director of Dental Materials, a required core course for all third-year dental students at the UConn Health School of Dental Medicine.
Journal Articles
- Tricolor Transgenic Murine Model for Studying Growth Plate Injury.
Sun, Hui; Patel, Natasha; Ridwan, Sharif M; Lottinger, Christy; Chen, Li; Rowe, David; Kuhn, Liisa Journal of visualized experiments : JoVE 2024 Sep;(211):
- Tri-color transgenic murine model for studying growth plate injury.
Sun H, Patel N, Lottinger C, Ridwan S, Chen L, Rowe D, and Kuhn LT. Journal of Visualized Experiments (JOVE), under review. 2024 Feb;
- One‐pot synthesis of bioinspired peptide‐decorated apatite nanoparticles for nanomedicine.
Guérin M, Lebrun A, Kuhn LT, Azaïs T, Laurent G, Marsan O, Drouet C, Subra G. Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2306358
- Controlled Self-Assembly of DNA-Mimicking Nanotubes to Form a Layer-by-Layer Scaffold for Homeostatic Tissue Constructs
Zhou L, Zhang W, Lee J, Kuhn LT, and Chen Y. ACS Applied Materials & Interfaces 2021 Nov;13(43):51321-51332
- Endogenous FGF-2 levels impact FGF-2/BMP-2 growth factor delivery dosing in aged murine calvarial bone defects.
Kuhn LT, Peng T, Gronowicz G and Hurley MM. Journal of Biomedical Materials Research. Part A 2021 Jun;
- Self-assembled biomimetic nano-matrix for stem cell anchorage.
Zhou L, Yau A, Yu H, Kuhn LT, Guo W, Chen Y. Journal of Biomedical Materials Research. Part A 2020 Apr;108(4):984-991
- Cell type influences local delivery of biomolecules from a bioinspired apatite drug delivery system.
Alhamdi J, Jacobs E, Gronowicz G, Benkirane-Jessel N, Hurley M, and Kuhn LT. Materials. 2018 Sep;11(9):
- Controlled M1-to-M2 transition of aged macrophages by calcium phosphate coatings.
Alhamdi JR, Peng T, Al-Naggar IM, Hawley KL, Spiller KL, and Kuhn LT. Biomaterials 2018 Jul;
- Calvarial bone regeneration is enhanced by sequential delivery of FGF-2 and BMP-2 from layer-by-layer coatings with a biomimetic calcium phosphate barrier layer.
Gronowicz G, Jacobs E, Peng T, Zhu L, Hurley M, and Kuhn LT. Tissue Engineering, Part A 2017 Sep;23(23-24):1490-1501
- Enhanced differentiation of dental pulp cells cultured on microtubular polymer scaffolds in vitro.
Haeri M, Sagomonyants K, Mina M, Kuhn LT, and Goldberg AJ. Regen Eng Transl Med 2017 Jun;3(2):94-105
- Implant-guided supracrestal alveolar bone growth using scaffolds, BMP-2, and novel scaffold-retaining device.
Wen B, Shafer D, Schleier P, Pendrys D, Kuhn LT, and Freilich M. Clinical Oral Implants Research 2017 Mar;281411-1420
- Layer-by-layer nanoparticle platform for cancer active targeting.
Suh MS, Shen J, Kuhn LT, and Burgess DJ. International Journal of Pharmaceutics 2017 Jan;517(1-2):58-66
- Comparison of bone morphogenetic protein-2 delivery systems to induce supracrestal bone guided by titanium implants in the rabbit mandible.
Wen B, Kuhn LT, Charles L, Pendrys D, Shafer D, and Freilich M. Clinical Oral Implants Research 2016 Dec;27(6):676-85
- Design and characterization of calcium phosphate ceramic scaffolds for bone tissue engineering.
Denry I and Kuhn LT. Dental materials : official publication of the Academy of Dental Materials 2016 Dec;32(1):43-53
- Biomimetic calcium phosphate/polyelectrolyte multilayer coatings for sequential delivery of multiple biological factors.
Jacobs E, Gronowicz G, Hurley M, and Kuhn LT. Journal of Biomedical Materials Research, Part A 2016 Dec;105(5):1500-1509
- Human biofield therapy does not affect tumor size but modulates immune responses in a mouse model for breast cancer.
Gronowicz G, Secor Jr ER, Flynn JR, and Kuhn LT. Journal of Integrative Medicine 2016 Sep;14(5):389-99
- Age-related changes in FGF-2, fibroblast growth factor receptors and β-catenin expression in human osteoblasts (mesenchyme-derived progenitor cells).
Hurley MM, Gronowicz G, Zhu L, Kuhn LT, Rodner C, and Xiao L. Journal of Cellular Biochemistry 2016 Mar;117(3):721-9
- Carboxymethyl hyaluronan-stabilized nanoparticles for anticancer drug delivery.
Woodman JL, Suh MS, Zhang J, Kondaveeti Y, Burgess DJ, White BA, Prestwich GD, and Kuhn LT. Int J Cell Biol 2015 Dec;249573
- Therapeutic touch has significant effects on mouse breast cancer metastasis and immune responses but not primary tumor size.
Gronowicz G, Secor Jr ER, Flynn JR, Jellison ER, and Kuhn LT. Evid Based Complement Alternat Med 2015 Dec;926565
- Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice.
Charles LF, Woodman JL, Ueno D, Gronowicz G, Hurley MM, and Kuhn LT. Experimental Gerontology 2015 Apr;6462-69
- Lithium-end-capped polylactide thin films influence osteoblast progenitor cell differentiation and mineralization.
Gomillion CT, Lakhman RK, Kasi RM, Weiss RA, Kuhn LT, and Goldberg AJ. Journal of Biomedical Materials Research, Part A 2015 Feb;103(2):500-10
- Optimizing BMP-2-induced bone repair with FGF-2.
Gronowicz G, Hurley MM, and Kuhn LT. The Journal of the American Academy of Orthopaedic Surgeons 2014 Oct;22(10):677-679
- A site-specific integrated Col2.3GFP reporter identifies osteoblasts within mineralized tissue formed in vivo by human embryonic stem cells.
Xin X, Jiang X, Wang L, Stover ML, Zhan S, Huang J, Goldberg AJ, Liu Y, Kuhn LT, Reichenberger EJ, Rowe DW, and Lichtler AC. Stem Cells Translational Medicine 2014 Aug;3(10):1125-37
- Fibroblast growth factor-2 isoform (low molecular weight/18 kDa) overexpression in preosteoblast cells promotes bone regeneration in critical size calvarial defects in male mice.
Xiao L, Ueno D, Catros S, Homer-Bouthiette C, Charles L, Kuhn LT, and Hurley MM. Endocrinology 2014 Mar;155(3):965-974
- Osteogenetic properties of electrospun nanofibrous PCL scaffolds equipped with chitosan-based nanoreservoirs of growth factors.
Ferrand A, Eap S, Richert L, Lemoine S, Kalaskar D, Demoustier-Champagne S, Atmani H, Mély Y, Fioretti F, Schlatter G, Kuhn LT, Ladam G, and Benkirane-Jessel N. Macromolecular Bioscience 2014 Jan;14(1):45-55
- Fibroblast growth factor-2 and bone morphogenetic protein-2 have a synergistic stimulatory effect on bone formation in cell cultures from elderly mouse and human bone.
Kuhn LT, Ou G, Charles L, Hurley MM, Rodner CM, and Gronowicz G. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2013 Oct;68(10):1170-1180
- Developmental-like bone regeneration using human embryonic stem cell-derived mesenchymal cells.
Kuhn LT, Liu Y, Boyd NL, Dennis JE, Jiang X, Xin X, Charles LF, Wang L, Aguila HL, Rowe DW, Lichtler AC, and Goldberg AJ. Tissue Engineering, Part A 2013 Aug;20(1-2):365-377
- Targeting tumor hypoxia with 2-nitroimidazoleindocyanine green dye conjugates.
Xu Y, Zanganeh S, Mohammad I, Aguirre S, Wang T, Yang Y, Kuhn LT, Smith M, and Zhu Q. Journal of Biomedical Optics 2013 Jun;18(6):66009
- Use of a perforated scaffold retaining abutment to achieve vertical bone regeneration around dental implants in the minipig.
Catros S, Wen B, Schleier P, Shafer D, Dard M, Obrecht M, Freilich M, Kuhn LT. Int J Oral Maxillofac Implants 2013 Apr;28(2):432-443
- Lectin concanavalin A coatings for rapid attachment of human embryonic stem cells.
Liu Y, Goldberg AJ, Aguila HL, and Kuhn LT. Open Journal of Biomedical Engineering 2013 Jan;1(1):6-14
- Modified hyaluronan hydrogels support the maintenance of mouse embryonic stem cells and human induced pluripotent stem cells.
Liu Y, Charles LF, Zarembinski TI, Johnson KI, Atzet SK, Wesselschmidt RL, Wight ME, and Kuhn LT. Macromolecular Bioscience 2012 Aug;12(8):1034-1042
- Implant-guided vertical bone growth in the mini-pig.
Freilich M, Wen B, Shafer D, Schleier P, Dard M, Pendrys D; Ortiz D; and Kuhn LT. Clinical Oral Implants Research. 2012 Jun;23(6):751-757
- One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating.
Liu Y, Goldberg AJ, Dennis JE, Gronowicz GA, and Kuhn LT. PLOS One 2012 Mar;7(3):e33225
- A comparison of roughened and alkaline treated titanium implants used to guide a new layer of bone growth on the rabbit mandible.
Karl M, Freilich MA, Wen B, Wei M, Shafer D, and Kuhn LT. Zeitschrift fur Zahnarztliche Implantologie (Journal of Dental Implantology). 2011 Dec;27(2):
- An evaluation of BMP-2 delivery from scaffolds with miniaturized dental implants in a novel rat mandible model.
Wen B, Karl M, Pendrys D, Shafer D, Freilich M, and Kuhn LT. Journal of Biomedical Materials Research – B Applied Biomaterials 2011 Dec;97(2):315-326
- Synthesis and fluorescent characteristics of imidazole-indocyanine green conjugates.
Pavlik C, Biswal N, Gaenzler FC, Morton MD, Kuhn LT, Claffey KP, Zhu Q, and Smith M. Dyes and Pigments 2011 Dec;899-15
- Imaging tumor hypoxia by near-infrared fluorescence tomography.
Biswal NC, Pavlik C, Smith MB, Aguirre A, Xu Y, Zanganeh S, Kuhn LT, Claffey KP, and Zhu Q. Journal of Biomedical Optics 2011 Jun;16(6):066009
- Fibroblast-growth factor 2 stimulates the proliferation of mesenchyme-derived progenitor cells from aging mouse and human bone.
Ou G, Charles LF, Matton SJ, Rodner C, Hurley M, Kuhn LT, and Gronowicz G. Journal of Gerontology: A Biol Sci Med Sci 2010 Dec;65(10):1051-1059
- A nondestructive method for evaluating in vitro osteoblast differentiation on biomaterials using osteoblast-specific fluorescence.
Kuhn LT, Liu Y, Advincula M, Wang YH, Maye PF, and Goldberg AJ. Tissue Engineering, Part C Methods 2010 Dec;16(6):1357-1366
- Pro416Arg cherubism mutation in Sh3bp2 knock-in mice affects osteoblasts and alters bone mineral and matrix properties.
Wang CJ, Chen IP, Koczon-Jaremko B, Boskey AL, Ueki Y, Kuhn LT, and Reichenberger EJ. Bone 2010 May;46(5):1306-1315
- Fabrication and characterization of hydroxyapatite-coated polystyrene disks for use in osteoprogenitor cell culture.
Goldberg AJ, Liu Y, Advincula MC, Gronowicz G, Habibovic P, and Kuhn LT. Journal of biomaterials science - polymer edition 2010 Jan;21(10):1371-1387
- Implant system for guiding a new layer of bone: computed microtomography and histomorphometric analysis in the rabbit mandible.
Freilich M, Shafer D, Wei M, Kompalli R, Adams D, and Kuhn LT. Clinical Oral Implants Research 2009 Feb;20(2):201-207
- Growth of new bone guided by implants in a murine calvarial model.
Freilich M, Patel CM, Wei M, Shafer D, Schleier P, Hortschansky P, Kompali R, and Kuhn LT. Bone 2008 Oct;43(4):781-788
- A comparison of the physical and chemical differences between cancellous and cortical bovine bone mineral at two ages.
Kuhn LT, Grynpas MD, Rey C, Wu Y, Ackerman JL, and Glimcher MJ. Calcified Tissue International 2008 Aug;83(2):146-154
- Chemotherapy drug delivery from calcium phosphate nanoparticles.
Cheng X and Kuhn LT. International Journal of Nanomedicine 2007 Dec;2(4):667-74
- Effects of the physico-chemical nature of two biomimetic crystals on the innate immune response.
Ramesh M, Turner LT, Yadav R, Rajan TV, Vella AT, and Kuhn LT. International Immunopharmacology 2007 Dec;7(13):1617-1629
- A novel surgical approach for treatment of class II furcation defects using marginal periosteal membrane.
Hazzaa HH, El Adawy H, and Magdi HM. Journal of the International Academy of Periodontology 2005 Jan;17(1):20-31
- Interactions of cisplatin with calcium phosphate nanoparticles: in vitro controlled adsorption and release.
Barroug A, Kuhn LT, Gerstenfeld LC, and Glimcher MJ. Journal of Orthopaedic Research 2004 Jul;22(4):703-708
- Size and shape of mineralites in young bovine bone measured by atomic force microscopy.
Tong W, Glimcher MJ, Katz JL, Kuhn LT, and Eppell SJ. Calcified Tissue International 2003 Dec;72592-598
- Shape and size of isolated bone mineralites measured using atomic force microscopy.
Eppell SJ, Tong W, Katz JL, Kuhn LT, and Glimcher MJ. Journal of Orthopaedic Research 2001 Dec;191027-1034
- Evidence of hydroxyl-ion deficiency in bone apatites: an inelastic neutron scattering study.
Loong CK, Rey C, Kuhn LT, Combes C, Wu Y, Chen SH, and Glimcher MJ. Bone 2000 Dec;26(6):599-602
- Structure, composition, and maturation of newly deposited calcium-phosphate crystals in chicken osteoblast cell cultures.
Kuhn LT, Wu Y, Rey C, Gerstenfeld L, Grynpas M, Ackerman J, Kim HM, and Glimcher MJ. Journal of Bone and Mineral Research 2000 Dec;15(7):1301-1309
- Mechanical properties and the hierarchical structure of bone.
Rho JY, Kuhn-Spearing LT, and Zioupos P. Medical Engineering and Physics 1998 Dec;2092-102
- A biomimetic example of brittle toughening: I. steady state multiple cracking.
Kessler H, Ballarini R, Mullin RL, Kuhn LT, and Heuer AH. J of Computational Materials Science 1996 Dec;5157-166
- Fracture mechanisms of the strombus gigas conch shell: implications for the design of brittle laminates.
Kuhn-Spearing LT, Kessler H, Spearing SM, Ballarini R, and Heuer AH. Journal of Materials Science 1996 Dec;316583-6594
- Raman spectra of vateritic calcium carbonate.
Behrens G, Kuhn LT, Ubic R, and Heuer AH. Spectroscopy Letters 1995 Dec;28(6):983-995
- The effect of organic macromolecules on the vaterite to calcite transformation.
Kuhn Spearing LT, Sarig S, Fink DJ, and Heuer AH. S: Biomolecular Materials by Design, eds. H. Bayley, D. Kaplan, and M. Navia (Mat. Res. Soc. Proc.). 1994 Dec;330127-132
- Yielding of metal powder bonded by isolated contacts.
Fleck NA, Kuhn LT, and McMeeking RM. Journal of Mechanics and Physics of Solids 1992 Dec;40(5):1139-1162
- A diffusional creep law for powder compacts.
McMeeking RM and Kuhn LT. Acta Metallurgica et Materialia 1991 Dec;40(5):961-969
- A model for powder consolidation.
Kuhn LT, McMeeking RM, and Lange FF. Journal of the American Ceramic Society 1991 Dec;74(3):682-685
- Power law creep of metal powder bonded by isolated contacts.
Kuhn LT and McMeeking RM. International Journal of Mechanical Sciences 1991 Dec;34563-573
Book Chapters
- Biomaterials
Kuhn LT and Tang-Schomer M Introduction to Biomedical Engineering, 4th edition 2023 Dec;
- Chapter 3.1.8: Role of Standards for Testing and Performance Requirements of Biomaterials
Wagner W, Sakiyama-Elbert S, and Zhang G Biomaterials Science, An Introduction to Materials in Medicine, 4th edition 2020 Dec;
- Chapter 65: Dental implant guided bone tissue engineering.
Wen B, Freilich M, and Kuhn LT. Stem Cell Biology and Tissue Engineering in Dental Sciences 2015 Dec;
- Chapter 14: Evaluation of bio-inspired materials for mineralized tissue regeneration using type I collagen reporter cells.
Kuhn LT, Jacobs E, and Goldberg AJ. Bio-Inspired Materials for Biomedical Engineering 2014 Dec;
- Chapter 5: Biomaterials.
Kuhn LT and Goldberg AJ. Regenerative Engineering 2013 Dec;
- Chapter 5: Biomaterials.
Kuhn LT. Introduction to Biomedical Engineering, 3rd Edition 2012 Dec;
- Chapter 6: Biomaterials.
Kuhn LT. Introduction to Biomedical Engineering 2005 Dec;
- Chapter 8: Bone mineralization.
Kuhn LT. Encyclopedia of Materials: Science and Technology 2001 Dec;787-794
- Biomimetic Processing of Ceramics.
Kuhn-Spearing LT and Heuer AH. Encyclopedia of Applied Physics 1999 Dec;27-45
- Biomimetic strategies and materials processing.
Kuhn LT, Fink DJ, and Heuer AH. Biomimetic Approaches in Materials Science 1995 Dec;41-68
Abstracts
- Calcium phosphate/polyelectrolyte multilayer coatings for sequential delivery of multiple growth factors.
Jacobs E, Hurley M, Gronowicz G, and Kuhn LT. Frontiers Bioeng Biotechnol. Conference Abstract, 10th World Biomaterials Congress 2016 May;
- Visual monitoring of osteoblast progenitor cell differentiation on dewetted PLA thin films.
Lakhman R, O’Brien K, Kasi R, Weiss RA, Kuhn LT, and Goldberg AJ. Materials Research Society 2011 Apr;
- Advanced micro- and nanofabrication technologies for tissue engineering.
Shapira A, Kim DH, and Dvir T. Biofabrication 2011 Jan;6(2):020301
- Substantial mouse bone repair by osteo-chondrogenic progenitors derived from hESCs.
Liu Y, Boyd NL, Dennis JE, Goldberg AJ, Stice SL, and Kuhn LT. Regenerative Medicine:Innovations for Clinical Applications 2011 Jan;
- Substantial mouse calvarial bone defect healing by human embryonic stem cells.
Kuhn LT, Liu Y, Boyd N, Dennis J, Aguila HL, and Goldberg AJ. StemCONN 2011 2011 Jan;
- Substantial mouse calvarial bone defect healing by human embryonic stem cells.
Kuhn LT, Liu Y, Boyd NL, Dennis J, Aguila H, Lichtler A, and Goldberg AJ. Orthopedic Research Society 2011 Jan;
- Varying PLA functionality and texture to influence osteoprogenitors.
Lakhman R, O’Brien K, Kasi R, Weiss RA, Kuhn LT, Mina M, and Goldberg AJ. Academy of Dental Materials 2010 Oct;
- Non-physiological mineral deposition in vitro by primary human osteoblasts under osteogenic conditions.
Charles LF, Woodman JL, Goldberg AJ, Gronowicz GA, and Kuhn LT. Proceedings of the IEEE 36th Annual Northeast Bioengineering Conference 2010 Mar;
- Osteogenesis by hESCs after cell culture on fibrillar Type I collagen coatings.
Liu Y, Goldberg AJ, Elliott JT, Plant AL, and Kuhn LT. Proceedings of the IEEE 36th Northeast Bioengineering Conference 2010 Mar;
- Fibrillar collagen thin films promote early osteogenesis.
Liu Y, Goldberg AJ, Maye PF, Advincula M, and Kuhn LT. American Association for Dental Research Annual Meeting 2010 Jan;
- Variance of Extracel hydrogel compositions and the osteogenic effects on GFP-reporter preosteoblasts.
Liu, Y.; Goldberg, A.J. and Kuhn L.T. Society for Biomaterials 2010 Jan;
- Biomimetic method for coating tissue culture polystyrene with carbonated hydroxyapaptite.
Kuhn LT, Advincula MC, Liu Y, Gronowicz G, Habibovic P, and Goldberg AJ. J Dent Res 2009 Apr;88
- Reduction of chemotherapy side effects and targeted inhibition of lymph node metastasis with a calcium phosphate nanoparticle delivery vehicle. 31st Annual San Antonio Breast Cancer Symposium, San Antonio, TX. Dec 10-14, 2008.
Kuhn L, Wen B, and Piteo P. Cancer Research 2009 Jan;69(2 Supplement):2135
- Differential effects of fibrillar and non-fibrillar collagens on osteogenesis of GFP-reporter preosteoblasts.
Liu Y, Advincula M, Goldberg AJ, and Kuhn LT. New England Musculoskeletal Institute Research Day 2009 Jan;
- Fluorescent quantification of osteogenesis of GFP-transgenic mouse calvarial osteoblasts on biomimetic coatings.
Liu Y, Advincula M, Wang YH, Goldberg AJ, and Kuhn LT. Society for Biomaterials 2009 Jan;
- Fluorescent quantification of osteogenesis using GFP-transgenic mouse reporter cell technology.
Kuhn LT, Goldberg AJ, Liu Y, and Rowe DW. Regenerative Medicine-Advancing Next Generation Therapies 2009 Jan;
- Quantitative evaluation of supracrestal bone growth around dental implants. International Association for Dental Research Annual Meeting, Toronto, Ontario, Canada. July 2-5, 2008.
Kuhn LT, Wen B, Obrecht M, Stauber M, Jorgenson K, Shafer D, and Freilich M. J Dent Res 2008 Jul;87(Spec Iss B):
Conference Papers
- Calcium phosphate: carrier for therapeutic agents.
Lee D, Tofighi A, Kuhn LT, and Rey C. 123-190
- Carbonated apatite nanocrystals from bone in synthesis and processing of nanocrystalline powder.
Kuhn-Spearing LT, Rey C, Kim H-M, and Glimcher MJ. 57-68
- Chemoradiotherapy of ME-180 tumors with an intratumoral cisplatin/calcium phosphate drug delivery system.
Santiago F, Campbell S, Dowsett R, and Kuhn LT. Proceedings of the IEEE 32nd Northeast Bioengineering Conference 2006189-190
- Constitutive models for the deformation of powder compacts in computational and numerical techniques.
Kuhn LT, Xu J, and McMeeking RM.
- Eggshell assembly - a model for biomimetic ceramic production in quality of poultry products.
Fink DJ, Kuhn LT, Caplan AI, and Heuer AH. A1-A6
- Evaluation of lymphatic metastasis using calcium phosphate/cisplatin nanoconjugates.
Piteo P, Wen B, and Kuhn LT.
- Improvement of alveolar bone height using novel graft placement.
Freilich MA, Wei M, Iddir S, Kuhn LT, and Shafer DM. 284-286, 889-892
- Modelling powder consolidation.
Kuhn LT, McMeeking RM, and Lange FF. 331-338
- Osteoinductive composites of calcium phosphate cement and demineralized bone matrix. Poster 1429.
Rosenberg AD, Kuhn LT, Gilles de Pelichy L, and Jolette J. 32
Editorials
- Editorial: Enabling biomaterials for new biomedical technologies and clinical therapies.
Uludag H, Pandit A, and Kuhn LT. Frontiers in Bioengineering and Biotechnology. 2020 Jun;8559
Erratums
- Erratum: A comparison of the physical and chemical differences between cancellous and cortical bovine bone mineral at two ages.
Kuhn LT, Grynpas MD, Rey CC, Wu Y, Ackerman JL, and Glimcher MJ. Calcified Tissue International 2009 Jan;83(2):146-154
Letters
- Response to the letter "Age and site should be considered when investigating the effect of growth factors on human bone-derived cells."
Gronowicz G and Kuhn LT. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2014 Jul;69(9):1092-3